Structural and Functional Analyses of MRS (Major Repeated Sequnece) in Candida albicans-Application for Genotyping and the Eternal Way to the Complete Genome Sequence-

DOI Web Site PubMed 63 References Open Access
  • Chibana Hiroji
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University
  • Mikami Yuzuru
    Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University

Bibliographic Information

Other Title
  • Ｃａｎｄｉｄａ　ａｌｂｉｃａｎｓにおけるＭＲＳ（Ｍａｊｏｒ　ｒｅｐｅａｔｅｄ　ｓｅｑｕｅｎｃｅ）の構造と機能解析―遺伝子型解析への応用と全ゲノム解析の永い道のり―
  • Candida albicans ニ オケル MRS(Major repeated sequence)ノ コウゾウ ト キノウ カイセキ : イデンシガタ カイセキ エ ノ オウヨウ ト ゼン ゲノム カイセキ ノ ナガイ ミチノリ
  • —Application for Genotyping and the Eternal Way to the Complete Genome Sequence—
  • ―遺伝子型解析への応用と全ゲノム解析の永い道のり―

Search this article

Description

There are several different types of repeated sequences in the genome of Candida albicans, including the MRS (Major repeated sequence). In 2004, the whole genome sequence of C. albicans was published. Assembly of the sequences to chromosomal length contigs was not achieved, mainly due to interruption of the sequences by MRS. However, MRS including Ca3, 27A and RPS have been playing important roles in a number of epidemiological research studies and basic biological investigations into C. albicans chromosome loss events and associated phenotypic changes. Here we summarize structural analyses from subrepeat sequences to the chromosome level, and functional analyses of MRS.

Journal

References(63)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top