Relationship between Sleep Disordered Breathing and Lifestyle-Related Illness

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  • OKADA Mitsuyo
    Department of Internal Medicine, Shinshu University School of Medicine
  • TAKAMIZAWA Akemi
    Department of Respiratory, JA Nagano Koseiren Shinonoi General Hospital
  • TSUSHIMA Kenji
    Department of Internal Medicine, Shinshu University School of Medicine
  • URUSHIHATA Kazuhisa
    Department of Internal Medicine, Shinshu University School of Medicine
  • FUJIMOTO Keisaku
    Department of Internal Medicine, Shinshu University School of Medicine
  • KUBO Keishi
    Department of Internal Medicine, Shinshu University School of Medicine

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  • 睡眠呼吸障害と生活習慣病との関連―１泊２日人間ドック受診者を対象とした無作為試験―
  • スイミン コキュウ ショウガイ ト セイカツ シュウカンビョウ ト ノ カンレン 1パク 2ニチ ニンゲン ドック ジュシンシャ オ タイショウ ト シタ ムサクイ シケン

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Abstract

In order to examine the relationship between sleep disordered breathing (SDB) and lifestyle-related illness, 207 men who were randomly selected from 824 men admitted to Shinonoi hospital for health screening were subjected to short-form polysomnography for one night. Fifty-nine men showed moderate to severe SDB of more than 15 events of apnea and hypopnea per hour (AHI), and had a significantly higher prevalence of hypertension, glucose intolerance, liver dysfunction, hypercholesteremia, and showed significant increases in blood pressure and HbA1c compared with men without SDB (AHI<5 events/hour). Also, when the obese men were excluded from the analysis, the prevalence of hypertension was still higher in the moderate to severe SDB group than in the group without SDB. These findings suggest that there is a close association in men between SDB and lifestyle-related illness such as hypertension, hyperlipidemia, glucose intolerance, and liver dysfunction.

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