Clinical study of 80 cases of mallory-weiss syndrome with special reference to the associated lesions of the upper gastrointestinal tract.

DOI
  • NAKAMURA Tsuneya
    Second Department of Internal Medicine, Nagoya University School of Medicine
  • NAKAZAWA Saburo
    Second Department of Internal Medicine, Nagoya University School of Medicine
  • KAWAGUCHI Shinpei
    Second Department of Internal Medicine, Nagoya University School of Medicine
  • YOSHINO Junji
    Second Department of Internal Medicine, Nagoya University School of Medicine
  • KAWASE Shuuji
    Second Department of Internal Medicine, Nagoya University School of Medicine
  • KOIKE Mitsumasa
    Second Department of Internal Medicine, Nagoya University School of Medicine
  • OHTA Hirosato
    Second Department of Internal Medicine, Nagoya University School of Medicine
  • KANAMORI Yoko
    Second Department of Internal Medicine, Nagoya University School of Medicine
  • GOTO Hidemi
    Second Department of Internal Medicine, Nagoya University School of Medicine

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Other Title
  • Mallory‐Weiss症候群80例の検討  特に上部消化管合併病変に注目して

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Abstract

Clinical features of 80 cases of Mallory-Weiss syndrome were analyzed, especially regarding the associated lesions of the upper gastrointestinal tract. Sixty cases were accompanied with nausea or vomiting, and in 32 cases of them (53%) the causes of the prodromal symptoms were unclear. Forty cases were accompanied with the associated lesions and in 27 cases of them the causes of the prodromal symptoms were unclear. Twenty one cases of the 27 (78%) had the prodromal symptoms. It is supposed that the associated lesions may cause mucosal lacerations of Mallory-Weiss syndrome by inducing the prodromal symptoms. As to the number of mucosal laceration, there were a laceration in 52 cases, two lacerations in 13, three in 2. The lacerations were located straddling on the esophagus and the stomach in 29 cases, and were commonly seen on the lesser curvature and the posterior wall. In 40 cases, the lacerations got to the scarring stage endoscopically. In 32 of the 40 cases, the healing was shown within 3 weeks. Although 19 cases required blood transfusion, only 5 cases needed over 1000 ml of blood. The age of these 5 cases ranged from 51 to 72 with the mean age of 64.4. All were cured without operation.

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