CUTANEOUS CROHN'S DISEASE WITH ISOLATED COLONIC INVOLVEMENT DIAGNOSED IN THE EARLY PHASE ON SKIN BIOPSY

DOI 20 References
  • MIWA Naoyuki
    Department of Internal Medicine, Tokyo Saiseikai Central Hospital.
  • NAKAZAWA Atsushi
    Department of Internal Medicine, Tokyo Saiseikai Central Hospital.
  • EI Shigenori
    Department of Internal Medicine, Tokyo Saiseikai Central Hospital.
  • HATOGAI Ken
    Department of Internal Medicine, Tokyo Saiseikai Central Hospital.
  • MAEDA Norio
    Department of Internal Medicine, Tokyo Saiseikai Central Hospital.
  • SHIGEMATSU Takeharu
    Department of Internal Medicine, Tokyo Saiseikai Central Hospital.
  • MIZUKI Akira
    Department of Internal Medicine, Tokyo Saiseikai Central Hospital.
  • MUKAI Kiyoshi
    Department of Pathology, Tokyo Saiseikai Central Hospital.
  • TSUKADA Nobuhiro
    Department of Internal Medicine, Tokyo Saiseikai Central Hospital.

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Other Title
  • 早期の皮膚生検が診断の一助となったCrohn病の1例

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Abstract

A 28 year-old female complained of fever, arthralgia, diarrhea, and painful erythema nodosum on the lower legs. Although an atypical shallow, longitudinal ulcer was found on colonoscopy, the histological findings did not suggest Crohn's disease. Nevertheless, on skin biopsy, multinucleated giant-cell granulomas were noted in the subcutaneous tissue. Therefore, Crohn's disease with isolated colonic involvement and extra-intestinal cutaneous manifestations was diagnosed. A skin biopsy should be done in the early phase if Crohn's disease with skin lesions is suspected, since it is useful for making the diagnosis.

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