Absence of Synergistic Toxicity of Two Food Additives, Sodium Dehydroacetate and Dibutyl Hydroxy Toluene, in Rats Treated Orally for 6 Months

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  • デヒドロ酢酸ナトリウムとジブチルヒドロキシトルエンの併用投与における毒性
  • デヒドロ サクサン ナトリウム ト ジブチルヒドロキシトルエン ノ ヘイヨウ
  • Studies on Synergistic Toxicity of Food Additives. II
  • 食品添加物の相乗毒性に関する研究 (第2報)

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Toxicological potentiation of two food additives was investigated in male and female Wistar rats given sodium dehydroacetate (DHA-Na) and dibutyl hydroxy toluene (BHT) in the diet for 6 months. The concentrations of the samples in the diet were 0 (control and pair feeding control), DHA-Na 0.05, 0.15 and 0.5%, BHT 0.1, 0.3 and 1%, DHA-Na 0.05%+BHT 0.1%, DHA-Na 0.5%+BHT 0.1% and DHA-Na 0.05%+BHT 1%. Under the present experimental conditions, no marked potentiation of toxicity was observed in the combination of DHA-Na and BHT.

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