Antigenicity and Phototoxicity of Water-soluble Extract from Salacia reticulata (Celastraceae).
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- SHIMODA Hiroshi
- Morishita Jintan Co. Ltd.
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- ASANO Ikuko
- Hashima Laboratory, Nihon Bioresearch Inc.
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- YAMADA Yasushi
- Hashima Laboratory, Nihon Bioresearch Inc.
Bibliographic Information
- Other Title
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- ニシキギ科植物サラシア・レティキュラータ（Ｓａｌａｃｉａ ｒｅｔｉｃｕｌａｔａ）水抽出エキスの抗原性及び光毒性
- ニシキギカ ショクブツ サラシア レティキュラータ Salacia reticulata ミズ チュウシュツ エキス ノ コウゲンセイ オヨビ ヒカリ ドクセイ
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Abstract
The antigenicity and phototoxicity of water-soluble extract from Salacia reticulata (SRE) were examined in guinea pigs. In a study of active systemic anaphylaxis reaction, neither the oral administration group (64 or 320 mg/kg, 5 times/week, 3 weeks) nor the subcutaneous administration group (64 mg/kg, 1 time/week, 3 weeks) exhibited any anaphylactic reaction. Moreover, sensitization with serum obtained from these animals did not induce passive cutaneous anaphylaxis reaction in normal animals. In a phototoxicity study, oral administration of SRE (320 mg/kg) induced neither erythema nor edema. These results suggest that SRE is not antigenic or phototoxic.
Journal
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- Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)
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Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi) 42 (2), 144-147, 2001
Japanese Society for Food Hygiene and Safety
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Details 詳細情報について
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- CRID
- 1390282679202165504
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- NII Article ID
- 10009305984
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- NII Book ID
- AN00117741
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- COI
- 1:CAS:528:DC%2BD3MXjs1Cltbw%3D
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- ISSN
- 18821006
- 00156426
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- NDL BIB ID
- 5755345
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- PubMed
- 11486382
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- Text Lang
- ja
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed
