Determination of Rodenticide Tetramethylenedisulfotetramine (Tetramine) in Processed Foods by Gas Chromatography-Tandem Mass Spectrometry

DOI JASI Web Site Web Site PubMed 5 References

Bibliographic Information

Other Title
  • GC-MS/MSを用いた加工食品中の殺鼠剤テトラメチレンジスルホテトラミン（テトラミン）分析法

Search this article

Description

<p>A GC-MS/MS method for determination of the rodenticide tetramethylenedisulfotetramine was developed. Tetramethylenedisulfotetramine was extracted from the sample with ethyl acetate in the presence of anhydrous sodium sulfate. Then, an aliquot of the extract was evaporated under vacuum, followed by acetonitrile/hexane partitioning, and cleanup with a tandem graphitized carbon/primary secondary amine (PSA) column, prior to GC-MS/MS analysis. The recoveries from 10 processed foods, all of which were fortified at 0.1 mg/kg, were in the range of 85–96%, and the relative standard deviations were less than 7%. The proposed method effectively removed co-extracted matrix components, and matrix effects were negligible in the GC-MS/MS analysis. In addition, no interfering peaks were found in the chromatograms of the blank samples at the retention time of tetramethylenedisulfotetramine, indicating that the method is highly selective. Overall results suggest that the proposed method is suitable for determining tetramethylenedisulfotetramine contained in processed foods.</p>

Journal

References(5)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top