Residue Studies in Egg on Pyrimethamine given with Feed

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  • 給与飼料中のピリメタミンの鶏卵への移行残留
  • キュウヨ シリョウチュウ ノ ピリメタミン ノ ケイラン エ ノ イコウ ザン

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Laying hens were divided into four groups, and the 1st control group was fed pyrimethamine-free diet during the experimental period. The 2nd, 3rd and 4th groups were fed freely with the diet containing 0.1, 1 and 10ppm pyrimethamine, respectively, for three weeks and, thereafter, given the pyrimethamine-free diet.<br>During the medication period, in the 4th group, 3.33 and 0.13ppm pyrimethamine were found in yolk and albumen, respectively. In the 3rd group, 0.69 and 0.04ppm pyrimethemine were detected in yolk and albumen, respectively. In the 2nd group, 0.03ppm pyrimethamine was found in yolk, but none was detected in albumen during the experimental period.<br>In the 4th group, pyrimethamine in yolk and albumen decreased to below the detection limit on the 12th day and 5th day, after the withdrawal of medication, respectively. In the 3rd group, pyrimethamine in yolk and albumen decreased to below the detection limit on the 9th day after the withdrawal of medication and on the 19th day after the beginning of medication, respectively. In the 2nd group, pyrimethamine in yolk decreased to below the detection limit on the 2nd day after withdrawal of medication.

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