HPLCによる食品中のアセスルファムK, サッカリン及びアスパルテームの分析法

書誌事項

タイトル別名
  • Determination of Acesulfame K, Saccharin and Aspartame in Various Foods by HPLC
  • HPLC ニヨル ショクヒンチュウ ノ アセスルファム K サッカリン オヨビ

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説明

Method for the determination of acesulfame K (AK), saccharin (SA) and aspartame (APM) in various foods was investigated. Chopped or homogenized samples were packed with 0.01N hydrochloric acid containing 10% sodium chloride into cellulose tubing and dialyzed against 0.01N hydrochloric acid for 24-48 hours. For the detection of AK and SA, the dialyzate was analysed directly by HPLC on a Cosmosil 5NH2 column using a mobile phase of methanol-1% phosphoric acid (6:4) with detection at 230nm. For APM, the dialyzate was passed through a Sep-pak Vac C18 cartridge. The cartridge was washed with water and a mixture of methanol-water (2:8). APM was eluted with a mixture of methanol-1% phosphoric acid (3:7). It was separated on a Cosmosil 5C18-AR column using a mobile phase of methanol-0.02M phosphate buffer pH 4.0 (1:3) with detection at 210nm.<br>The recoveries of AK, SA and APM added to various foods were 94.3-100.4%, 80.4-99.6% and 90.8-101.7%, respectively. The detection limits of AK and APM were 10μg/g and that of SA was 5μg/g.

収録刊行物

  • 食品衛生学雑誌

    食品衛生学雑誌 37 (2), 91-96_1, 1996

    公益社団法人 日本食品衛生学会

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