Responses of the Human Testicular Capsule to Electrical Stimulation and to Autonomic Drugs

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  • RIKIMARU AKIRA
    Department of Applied Physiology Tohoku University School of Medicine
  • SHIRAI MASAFUMI
    Department of Applied Physiology Tohoku University School of Medicine Department of Urology Tohoku University School of Medicine

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Description

Responses of the isolated human testicular capsule to electrical stimulation and to some autonomic drugs were investigated. The capsule showed marked contractions to acetylcholine, noradrenaline and field stimulation with A. C. The response to acetylcholine was easily abolished by atropine, and the response to noradrenaline was reversed to relaxation after phentolamine. The contrac tion elicited by field stimulation was reduced by bretylium or tetrodotoxin which indicates the presence of adrenergic nerves in the capsule. It is suggested from these data that the human testicular capsule has many pharmacological similarities to that of rabbit.

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