Acceleration of Lipid Synthesis in Cultured Aortic Cells by Adenosine Phosphates

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  • MURATA KATSUMI
    Department of Physical Therapy and Medicine, University of Tokyo School of Medicine

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Effects of adenosine phosphates on lipid synthesis were studied in singular aortic cell culture system, in which a linear relation was shown between the 14C-acetate incorporation and incubation time over 6 hours. Adenosine triphosphate promoted 14C-acetate incorporation into cultured chick aortic intimal cells. The incorporation rate was greater in neutral fat and sterol fraction than in phospholipid fraction. Adenosine mono- and diphosphates as well as adenosine triphosphate accelerated lipid synthesis to the same extent in the aortic cell culture environment.

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