Platelet aggregation and plasma levels of beta-thromboglobulin in diabetes mellitus.
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- YAMADA KENICHI
- The Third Department of Internal Medicine, Tohoku University School of Medicine
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- MORI KAZUO
- The Third Department of Internal Medicine, Tohoku University School of Medicine
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- GOTO YOSHIO
- The Third Department of Internal Medicine, Tohoku University School of Medicine
書誌事項
- タイトル別名
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- Platelet Aggregation and Plasma Levels
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説明
YAMADA, K., MORI, K. and GOTO, Y. Platelet Aggregation and Plasma Levelsof Beta-Thromboglobulin in Diabetes Mellitus. Tohoku J. exp. Med., 1981, 135 (4), 423-429-In view of the tendency toward vascular complications in diabetesmellitus, we studied platelet aggregation and plasma beta-thromboglobulin (β-TG) levels in 35 healthy controls, 25 non-diabetic patients with ischemic heartdisease (IHD) and 85 diabetic patients. Blood platelets from diabetic patientsshowed no significant hyperaggregation induced by ADP, collagen or epinephrine, as compared with controls and non-diabetic patients with IHD, nor could bedemonstrated significant differences in platelet aggregation between diabetics withdiabetic microangiopathies and those without diabetic vascular complications.Significantly high levels of plasma β-TG were observed in diabetics in comparisonwith those in controls and non-diabetic patients with IHD. Patients withdiabetic microangiopathy had more significantly elevated β-TG levels thandiabetics without diabetic microangiopathies. Diabetics without diabeticmicroangiopathy had similar levels of β-TG to those of controls and non-diabeticpatients with IHD. High levels of plasma β-TG in diabetics with diabetic microangiopathyseem to indicate a platelet hyperfunction in vivo due to diabeticvascular complications, -platelet aggregation; diabetic microangiopathy; beta-thromboglobulin; diabetes mellitus; ischemic heart disease
収録刊行物
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 135 (4), 423-429, 1981
東北ジャーナル刊行会
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詳細情報 詳細情報について
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- CRID
- 1390282679217071744
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- NII論文ID
- 130003492902
- 40005306852
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- NII書誌ID
- AA00863920
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- COI
- 1:STN:280:DyaL387ltl2hsA%3D%3D
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- ISSN
- 13493329
- 00408727
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- NDL書誌ID
- 2477252
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- PubMed
- 6175049
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可