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- SEIJI MAKOTO
- Department of Dermatology, Tohoku University School of Medicine
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- ITAKURA HIDEKO
- Department of Dermatology, Tohoku University School of Medicine
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抄録
The effect of deoxycholate (DOC) on smooth-surface membranes was studied by means of electron microscopy. The smooth-surface membranes were isolated from Harding-Passey mouse melanomas and treated with 0.05% DOC. In the sectioned specimens, the untreated smooth-surface membranes appear as unit membranebound, closed vesicles. The unit membranes measure 50 Å across. The treated membranes showed significant vesiculation and swelling. In some parts many small vesicles are grouped in a cluster and enclosed by a membrane. A few to several unit membranes are stuck together to form myelin-like structures. In the negatively stained specimens, varying degrees of smooth-surface membrane vesiculation are apparent. Most large vesicles are found to exhibit myelin-like lamellar structures. From these observations, DOC appears to cause a vesiculation and swelling of the smooth-surface membranes but does not appear to destroy the unit membrane structure. There were a few myelin-like lamellar structures which were thought to have been produced by uniting several unit membranes.
収録刊行物
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 107 (2), 149-157, 1972
東北ジャーナル刊行会
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詳細情報 詳細情報について
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- CRID
- 1390282679217778432
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- NII論文ID
- 130003491665
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- NII書誌ID
- AA00863920
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- COI
- 1:CAS:528:DyaE38XltlGmtL0%3D
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- ISSN
- 13493329
- 00408727
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- NDL書誌ID
- 7672285
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- PubMed
- 4674432
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可