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- SEIJI MAKOTO
- Department of Dermatology, Tohoku University School of Medicine
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- TANAHASHI YOSHIO
- Department of Dermatology, Tohoku University School of Medicine
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- OIKAWA ATSUSHI
- Department of Dermatology, Tohoku University School of Medicine Biochemistry Divisition, National Cancer Center Research Institute
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Description
The relationship between cell proliferation and differentiation was studied using C341 cells' isolated from a culture cell line of mouse melanoma B-16. The C341 cells' rate of melanin formation is intimately related to active cell proliferation. The cells were examined with light and electron microscopes on the 4 th day of cultivation when the cells were proliferating exponentially and on the 7 th day when the culture was in the stationary phase. The 4-day-old culture consisted of dark, light and melanosome-containing cells. Melanosomes, mostly in the early stages of development, were found to be present in the light cells as well as in the melanosome-containing cells. In cells of the 7 th day culture, there were numerous melanosomes in various developmental stages and also melanosome complexes. The morphological evidence obtained is compatible with the biochemical evidence previously recorded.
Journal
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 107 (3), 203-216, 1972
Tohoku University Medical Press
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Keywords
Details 詳細情報について
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- CRID
- 1390282679217813120
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- NII Article ID
- 130003407495
- 40018681831
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- NII Book ID
- AA00863920
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- COI
- 1:STN:280:DyaE3s%2Fls1antw%3D%3D
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- ISSN
- 13493329
- 00408727
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- NDL BIB ID
- 7672295
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- PubMed
- 4674240
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed