A Lycium Chinense Miller Component Inducing Ovulation in Adult Female Rabbits

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  • SUZUKI MASAKUNI
    Department of Obstetrics and Gynecology, Tohoku University School of Medicine
  • OSAWA SHOGO
    Department of Obstetrics and Gynecology, Tohoku University School of Medicine
  • HIRANO MUTSUO
    Department of Obstetrics and Gynecology, Tohoku University School of Medicine

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Intravenous injection of the crude extract from Lycii folium among components of Lycium chinense Miller induced ovulation in the adult female rabbit. Chemical properties of the active component of this crude extract were investigated by dialysis, ninhydrin reaction, adsorption by charcoal, cellulose column chromatography with methanol solution, precipitation by methanol solution, Amberlite IR-410 and IR-4B column chromatography, DEAE cellulose chromatography, gel filtration with Sephadex G-25 and G-50, starch electrophoresis, etc. While the nature and the mechanism of action of this substance still remain unknown, the detection of a substance with such action in plants and the elucidation of its chemical properties may provide a step for future developments in reproductive physiology.

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