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- TOH KENTARO
- Department of Pathology, Sapporo Medical College
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- SATO NORIYUKI
- Department of Pathology, Sapporo Medical College
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- KIKUCHI KOKICHI
- Department of Pathology, Sapporo Medical College
書誌事項
- タイトル別名
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- Inhibition of Cellular DNA Synthesis by
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抄録
The DNA synthesis in syngeneie, allogeneic and xenogeneic cells was inhibited by peritoneal macrophages of normal WKA rats. This inhibitory effect of macrophages was found to be mediated by a soluble factor (MfID) released into a culture medium from macrophages which was heat-stable and non-dialyzable. The MfID was also responsible for the inhibition of lymphocyte DNA synthesis by MIX reaction. The action of MfID was indicated to suppress rather than to kill cell growth. It was interpreted that the inhibitory effect of macrophages on cellular DNA synthesis is their inherent property and macrophages may play the role of regulating the proliferation of lymphocytes and other cells.
収録刊行物
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 123 (4), 371-380, 1977
東北ジャーナル刊行会
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詳細情報 詳細情報について
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- CRID
- 1390282679217933696
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- NII論文ID
- 130003492385
- 40005306019
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- NII書誌ID
- AA00863920
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- COI
- 1:CAS:528:DyaE1cXhtF2huro%3D
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- ISSN
- 13493329
- 00408727
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- NDL書誌ID
- 1916936
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- PubMed
- 605447
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可