Insulin and Growth Hormone Secretion Stimulated by Intravenous Administration of Arginine in the Low Insulin Responders (Prediabetes ?)
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- TOYOTA TAKAYOSHI
- The Third Department of Internal Medicine, Hirosaki University School of Medicine
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- KUDO MIKIHIKO
- The Third Department of Internal Medicine, Hirosaki University School of Medicine
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- GOTO YOSHIO
- the Third Department of Internal Medicine, Tohoku University School of Medicine
書誌事項
- タイトル別名
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- Insulin and Growth Hormone Secretion St
この論文をさがす
抄録
Twelve apparently healthy subjects who showed a low insulin response to glucose were selected from two different age groups, 6 from youngers aged 19 to 22 and 6 from olders above 65 years old, and responses of insulin and growth hormone secretion to an intravenous administration of arginine were investigated. Incidence of low insulin responders, who showed the peak value of plasma insulin during GTT below 45μU/ml, was 9% among the young subjects and 24% among the old ones. Insulin secretion stimulated by arginine in 6 young low responders was not different from that in the control group matched with regard to age and body weight, and the values of growth hormone during arginine infusion were higher than those of the control group. In the old low insulin responders, insulin secretion stimulated by arginine was significantly lower than that in the control group, but the growth hormone secretion was not different from that in control. The present study showed that insulin and growth hormone secretion stimulated by arginine in young low-insulin-responders were different from those in the old ones. The low insulin responders are discussed in regard to prediabetes.
収録刊行物
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 123 (4), 359-364, 1977
東北ジャーナル刊行会
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詳細情報 詳細情報について
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- CRID
- 1390282679218020736
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- NII論文ID
- 130003492383
- 40005306026
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- NII書誌ID
- AA00863920
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- COI
- 1:CAS:528:DyaE1cXhtVaktbc%3D
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- ISSN
- 13493329
- 00408727
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- NDL書誌ID
- 1916943
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- PubMed
- 605445
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可