Effect of Section and Compression of the Optic Nerve on the ERG in the Rabbit

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  • Abe Nobuhiro
    Department of Ophthalmology, School of Medicine, Tohoku University Sendai

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1) The amplitude of the b-wave of the ERG in rabbits was found to increase following optic nerve section orr compression.<br> 2) After section of the optic nerve, either intracranial or intraorbital, the b-wave amplitude rose rapidly, up to the peak of 300-330% of the original amplitude, but hence decreased to 200-250% in 12 hours after the lesion of the optic nerve.<br> 3) After compression of the optic nerve, the rise of the b-wave amplitudc was slower. The peak value did not exceed the range of 180-250%, the subsequent drop being also less marked.<br> 4) The results showed no obvious difference whether the site of lesion orr the optic nerve was intracranial or intraorbital.<br> 5) The results of the present experiments are in line with those by Jacobsor et al., but not enough to justify their hypothesis.

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