Pathogenesis of Hypertension in Rabbits with Coarctation of the Abdominal Aorta
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- Fujii Jun
- Institute for Adult Diseases, Asahi Life Foundation
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- Murata Kazuhiko
- The Third Department of Internal Medicine Faculty of Medicine, University of Tokyo
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- Yamaguchi Hiroshi
- The Third Department of Internal Medicine Faculty of Medicine, University of Tokyo
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- Kuramochi Morio
- The Third Department of Internal Medicine Faculty of Medicine, University of Tokyo
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- Seki Akira
- The Third Department of Internal Medicine Faculty of Medicine, University of Tokyo
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- Ikeda Masao
- The Third Department of Internal Medicine Faculty of Medicine, University of Tokyo
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Abstract
Abdominal aorta of the rabbit was constricted with a silver clip above or below the renal arteries. A persistent rise of blood pressure was observed only in rabbits with aortic constriction above the renal arteries. The hypertension did not develop in rabbits with aortic constriction below the renal arteries. Plasma renin activity was within normal limits in 8 rabbits at acute stage of hypertension and was suppressed in 8 rabbits with chronic hypertension. The results indicate that the hypertension following aortic constriction is renal in origin and some renal mechanism not associated with renin-angiotensin system may be involved in it.
Journal
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 99 (2), 115-119, 1969
Tohoku University Medical Press
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Details 詳細情報について
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- CRID
- 1390282679220423168
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- NII Article ID
- 130003497995
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- NII Book ID
- AA00863920
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- COI
- 1:STN:280:DyaE3c%2FlvVKnug%3D%3D
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- ISSN
- 13493329
- 00408727
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- NDL BIB ID
- 8507910
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- PubMed
- 4311595
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed