Evaluation of Calcium Phosphate Coating Films on Titanium Fabricated Using RF Magnetron Sputtering
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- Ueda Kyosuke
- Department of Materials Processing, Tohoku University
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- Narushima Takayuki
- Tohoku University Biomedical Engineering Research Organization (TUBERO)
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- Goto Takashi
- Institute for Materials Research, Tohoku University
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- Katsube Tomoyuki
- Tohoku University Biomedical Engineering Research Organization (TUBERO)
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- Nakagawa Hironobu
- Graduate School of Dentistry, Tohoku University
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- Kawamura Hiroshi
- Graduate School of Dentistry, Tohoku University
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- Taira Masayuki
- Department of Dental Materials Science and Technology, Iwate Medical University School of Dentistry
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Abstract
Calcium phosphate coating films fabricated on commercially pure titanium (CP-Ti) substrates using radiofrequency (RF) magnetron sputtering were evaluated in vivo and in vitro for investigating their applications in dental and medical implants. For the in vitro evaluations of the calcium phosphate coating films, the bonding strength and alkaline phosphatase (ALP) activity were examined. The bonding strength of the coating films to a polished titanium plate exceeded 60 MPa. When compared with an uncoated titanium plate, the increase in the ALP activity of SaOS-2 cells (a well-characterized osteosarcoma human cell line exhibiting osteoblast-like properties) on a titanium plate coated with a calcium phosphate film was confirmed by a culture test. Titanium cylinders coated with an amorphous calcium phosphate film were implanted into the mandibles of beagle dogs. The percentage of bone-implant contact in coated titanium was greater than that in uncoated titanium.
Journal
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- MATERIALS TRANSACTIONS
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MATERIALS TRANSACTIONS 48 (3), 307-312, 2007
The Japan Institute of Metals and Materials
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Details 詳細情報について
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- CRID
- 1390282679228635776
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- NII Article ID
- 130004453461
- 10018734196
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- NII Book ID
- AA1151294X
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- COI
- 1:CAS:528:DC%2BD2sXksVOjsb8%3D
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- ISSN
- 13475320
- 13459678
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- HANDLE
- 10097/51945
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- NDL BIB ID
- 8670373
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- Text Lang
- en
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed