Polymer-functionalized Gold Nanoparticles as Versatile Sensing Materials

UEHARA Nobuo

doi:10.2116/analsci.26.1219

Polymer-functionalized Gold Nanoparticles as Versatile Sensing Materials

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UEHARA Nobuo

Department of Applied Chemistry, Graduate School of Engineering, Utsunomiya University

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In this brief review, gold nanoparticles conjugated with functional polymers are described from the viewpoint of application to sensing materials. The optical properties of gold nanoparticles, the synthesis of polymer-functionalized gold nanoparticles, and their analytical applications are discussed. Polymer-functionalized gold nanoparticles are categorized into two classes: biopolymer-conjugated gold nanoparticles and artificial-polymer conjugated gold nanoparticles. Fluorometric and colorimetric sensing using gold nanoparticles are focused; fluorometric detection enables us to exploit sensitive assays for practical use. Furthermore, chemical amplification using gold nanoparticles is also discussed for the sensitive probing.