Phenylboronic Acid-based <sup>19</sup>F MRI Probe for the Detection and Imaging of Hydrogen Peroxide Utilizing Its Large Chemical-Shift Change
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- NONAKA Hiroshi
- INAMORI Frontier Research Center, Kyushu University
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- AN Qi
- INAMORI Frontier Research Center, Kyushu University
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- SUGIHARA Fuminori
- Immunology Frontier Research Center, Osaka University
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- DOURA Tomohiro
- INAMORI Frontier Research Center, Kyushu University
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- TSUCHIYA Akira
- INAMORI Frontier Research Center, Kyushu University
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- YOSHIOKA Yoshichika
- Immunology Frontier Research Center, Osaka University
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- SANDO Shinsuke
- INAMORI Frontier Research Center, Kyushu University
Bibliographic Information
- Other Title
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- Phenylboronic Acid-based ¹⁹F MRI Probe for the Detection and Imaging of Hydrogen Peroxide Utilizing Its Large Chemical-Shift Change
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Abstract
Herein, we report on a new 19F MRI probe for the detection and imaging of H2O2. Our designed 2-fluorophenylboronic acid-based 19F probe promptly reacted with H2O2 to produce 2-fluorophenol via boronic acid oxidation. The accompanying 19F chemical-shift change reached 31 ppm under our experimental conditions. Such a large chemical-shift change allowed for the imaging of H2O2 by 19F chemical-shift-selective MRI.
Journal
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- Analytical Sciences
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Analytical Sciences 31 (4), 331-335, 2015
The Japan Society for Analytical Chemistry
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Details 詳細情報について
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- CRID
- 1390282679236783488
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- NII Article ID
- 130005061536
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- NII Book ID
- AA10500785
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- ISSN
- 13482246
- 09106340
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- NDL BIB ID
- 026322079
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- PubMed
- 25864678
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- Web Site
- http://id.ndl.go.jp/bib/026322079
- https://ndlsearch.ndl.go.jp/books/R000000004-I026322079
- https://link.springer.com/content/pdf/10.2116/analsci.31.331.pdf
- https://link.springer.com/article/10.2116/analsci.31.331/fulltext.html
- https://www.jstage.jst.go.jp/article/analsci/31/4/31_331/_pdf
- https://search.jamas.or.jp/link/ui/2015386060
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed
