Clinical Effectiveness of Kampo Medicine for Chronic Rhinitis and Sinusitis.

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  • 慢性鼻副鼻腔炎に対する漢方製剤の治療成績　辛夷清肺湯と四逆散の臨床効果
  • マンセイ フクビクウエン ニ タイスル カンポウ セイザイ ノ チリョウ セイ
  • ―辛夷清肺湯と四逆散の臨床効果―

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The clinical effectiveness of two different Kampo medicines, Tsumura Shin'i-seihai-to (TJ-104) and Shigyakusan (TJ-35) was evaluated in six patients with nonallergic chronic rhinitis and 61 with chronic sinusitis. The clinical effectiveness was graded according to four parameters; subjective symptoms, objective signs, the number of neutrophils in nasal smears, and rhinomanometric resistance. The therapeutic effect of TJ-104 was very good in 2.6%, moderate in 28.9%, slightin 23.7% while that of TJ-35 was very good in 3.7%, moderatein 29.6%, and slight in 25.9%. The differences between these two drugs are not statistically significant. With the improvement of nasal obstruction, the total rhinomanometric resistance decreased significantly in the TJ-104-treated patients (p<0.05). On the other hand, nasal obstruction did not show any correlation with rhinomanometric resistance after TJ-35 treatment.

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