The Positive Rate of Animal Allergen-specific IgE Antibodies Assessed in Nasal Allergy Patients Using the CAP-RAST System

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  • 川崎医科大学耳鼻咽喉科における抗原感作率の検討（第５報）―動物上皮抗原について―
  • 臨床 川崎医科大学耳鼻咽喉科における抗原感作率の検討(第5報)動物上皮抗原について
  • リンショウ カワサキイカ ダイガク ジビ インコウカ ニ オケル コウゲン カンサリツ ノ ケントウ ダイ5ホウ ドウブツ ジョウヒ コウゲン ニ ツイテ
  • ―動物上皮抗原について―

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Abstract

The prevalence of allergic disease has increased over the last 30 years in Japan. Enviromental factors such as house dust mites, air pollution and hygine customs associated with a westernized life style have been identified as possibly playing important roles in this increase. In Japan, the number of the households with pets has gradually increased, together with the number of people who have animal allergies. Many reports have discussed the relationships between animal-related allergies and asthma, but few have looked at allergic rhinitis. This study discusses the sensitization to animal allergens in 1262 patients treated at the Kawasaki Medical School Department of Otolaryngology between 2000 and 2008, who were tested for serum specific IgE antibodies using the CAP-radioallergosorbent (CAP-RAST) test. Sensitization to animal allergens was seen in 313 patients, 25.0% (male: 162 patients, female 151 patients). The highest sensitization was in teenagers, with the sensitization rate dropping concomitantly with age.<br> Animal-related allergies could thus become important antigens for future study.<br>

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