Pathological Findings of Renal Biopsy and Tonsils in of Patients with IgA Nephrophathy

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  • ＩｇＡ腎症腎生検組織像と口蓋扁桃組織像との対比
  • IgAジンショウジンセイケンソシキゾウ ト コウガイ ヘントウ ソシキゾウ ト ノ タイヒ

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Abstract

Background<br> IgA nephropathy treatment is usually planned and conducted based on pathological renal biopsy findings, laboratory data, and clinical symptoms. This involves improving the physical condition, diet therapy, and pharmacotherapy. Steroid pulse therapy following tonsillectomy is reported to be effective intending IgA nephropathy.<br> Methods<br> 24 patients that diagnosed with IgA nephropathy in renal biopsy underwent tonsillectomy. We them analyzed of the relationship between pathological renal biopsy findings and the tonsils of those with IgA nephropathy.<br> Results<br> No relationship was seen between the severity in pathological renal biopsy findings and the tonsils, thus showing typical morphological IgA nephrophath features.<br> Conclusions<br> Our study indicated no relationship between pathological renal biopsy findings and tonsils, suggesting that histological tonsils findings play no role in IgA nephrophath status and prognosis, Histological tonsils findings in IgA nephropathy differ from those in chronic tonsillitis, and the tonsils appear to be a unique organ causing initial and/or progressive events generating glomerular IgA deposits.<br>

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