Radiation-Induced Mucositis Pain in Mesopharyngeal and Hypopharyngeal Cancer
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- Takahashi Atsuhito
- Takahashi E.N.T Clinic
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- Shoji Kazuhiko
- Tenri Hospital
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- Iki Takehiro
- Kyoto University Graduate School of Medicine
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- Mizuta Masanobu
- Tenri Hospital
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- Matsubara Mami
- Tenri Hospital
Bibliographic Information
- Other Title
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- 中下咽頭癌放射線治療に伴う疼痛の検討
- 臨床 中下咽頭癌放射線治療に伴う疼痛の検討
- リンショウ チュウ カ イントウガン ホウシャセン チリョウ ニ トモナウ トウツウ ノ ケントウ
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Abstract
Radiation therapy in head and neck malignancy often triggers painful mucositis poorly controlled by nonsteroidal antiinflammatory drugs (NSAIDs). To better understand how radiation-induced pain develops over time, we studied numerical rating scale (NRS 0-5) pain scores in 27 subjects undergoing 60-72 Gy radiation therapy for newly diagnosed cancer—13 with mesopharx and 14 with hypopharynx. Mucositis severity was evaluated using Common Terminology Criteria for Adverse Events version3.0 (CTCAE v3.0) based on mucositis pain, analgesic administration, and oral feedings of our subjects, with 8 mesopharyngeal and 10 with hypopharyngeal cancer had been pain-free before radiation therapy. The mucositis and pain course was severer in mesopharyngesl than in hypopharyngeal cancer.<br> NSAIDs and opioid use was similar in both cancer types, which also required tube feeding in 7 subjects (38.9%).<br>
Journal
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- Practica Oto-Rhino-Laryngologica
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Practica Oto-Rhino-Laryngologica 103 (7), 657-663, 2010
The Society of Practical Otolaryngology
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Details 詳細情報について
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- CRID
- 1390282679240740864
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- NII Article ID
- 10029062570
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- NII Book ID
- AN00107089
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- ISSN
- 18844545
- 00326313
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- NDL BIB ID
- 10761736
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed