導入化学療法としてのＴＰＦ療法の安全性

DOI Web Site 被引用文献2件 参考文献9件

書誌事項

タイトル別名
  • Safety in the TPF-based Induction Chemotherapy for Head and Neck Cancer
  • 臨床 導入化学療法としてのTPF療法の安全性
  • リンショウ ドウニュウ カガク リョウホウ ト シテ ノ TPF リョウホウ ノ アンゼンセイ

この論文をさがす

抄録

Docetaxel, cisplatin, 5-fluorouracil (TPF)-based induction chemotherapy, while a durable, effective treatment for those with locally advanced squamous cell cancer of the head and neck, also induces toxicity problems, such as neutropenia.<br> We retrospectively compared TPF-based and cisplatin, 5-fluorouracil (PF)-based induction chemotherapy to clarify toxicity and safety.<br> Subjects numbered 54-19 undergoing TPF-based and 35 PF-based induction chemotherapy. Although the 2 groups did not differ significantly in other toxicities e.g., anorexia, diarrhea, and renal dysfunction, 89% of TPF group had grade 3-4 neutropenia significantly more often. Neutropenia was limited to a few days, making its occurrence easy to predict and its toxicity easier to manage in TPF-based induction chemotherapy.<br>

収録刊行物

被引用文献 (2)*注記

もっと見る

参考文献 (9)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ