書誌事項
- タイトル別名
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- Electroencephalographic studies on 2-methyl-4-amino-6-methoxy-s-triazine (CV 399)
- 2-Methyl-4-amino-6-methoxy-s-triazine CV399 ノ ノウハガクテキ ケンキュウ
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The effect of 2-methyl-4-amino-6-methoxy-s-triazine (CV 399) on the central nervous system was evaluted in cats. All the arousal response induced by midbrain reticular formation and posterior hypothalamus stimulation, the recruiting and augmenting responses by nucleus centralis medialis and leminiscus medialis stimulation and the spindle burst by nucleus caudate stimulation were not affected by this agent in curarized cats. Spontaneous EEG was not significantly changed by single administration of this agent in curarized cats and by repeated administration subacutely in the cat with chronically implanted electrodes. On the other hand, the agent markedly prolonged the duration of after-discharges produced by dorsal hippocampus and lateral amygdala stimulation in acute preparations including “enceéphale isolé” cats and chronic preparations. These results suggest that the limbic system is most susceptible to this agent and the effect on this system is probably related to the clinical psychostimulant action of this agent.
収録刊行物
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- 日本薬理学雑誌
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日本薬理学雑誌 66 (1), 76-82, 1970
公益社団法人 日本薬理学会
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詳細情報 詳細情報について
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- CRID
- 1390282679247760512
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- NII論文ID
- 130000757359
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- NII書誌ID
- AN00198335
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- COI
- 1:CAS:528:DyaE3MXktVeksrY%3D
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- ISSN
- 13478397
- 00155691
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- NDL書誌ID
- 8404043
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- PubMed
- 5464140
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可