A Case of Synovial Sarcoma of the Thyroid Gland Masquerading as Anaplastic Thyroid Carcinoma

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  • 未分化癌との鑑別に苦慮した甲状腺滑膜肉腫例
  • ミブンカガン ト ノ カンベツ ニ クリョ シタ コウジョウセンカツマク ニクシュレイ

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Abstract

<p>Synovial sarcoma is a relatively rare soft tissue sarcoma, most commonly occurring in the para-articular regions of the extremities and also in the head and neck region. To the best of our knowledge, there have been only six reports of thyroid synovial sarcoma in the medical literature. We report the case of a 49-year-old man who presented to us with the chief complaint of a cervical mass and hoarseness of the voice. Total thyroidectomy was performed, and anaplastic thyroid carcinoma was suspected on the basis of the histopathological findings. The patient received adjuvant concurrent chemoradiotherapy and adjuvant chemotherapy. One year 10 months after the surgery, the patient was diagnosed as having lung metastases, however, because of the atypically slow progression of these lesions, we reexamined the pathological diagnosis. Finally, the histopathological diagnosis of synovial sarcoma was confirmed by TLE1 immunohistochemistry. It was thought that the diagnosis was difficult, because synovial sarcoma of the thyroid gland is extremely rare, and histopathologically, poorly differentiated synovial sarcoma shows less specific features.</p>

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