Studies on the arsenic metabolism X. Effect of arsenite upon the spontaneous activity in rats

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  • ヒ素代謝に関する研究(第10報)　―ラットの自発運動におよぼすヒ素の影響について―
  • ヒソ タイシャ ニ カンスル ハキュウ 10 ラット ノ ジハツ ウンドウ ニ オヨボス ヒソ ノ エイキョウ ニ ツイテ

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After administering As2O3, 40 times the dose, 2.0 mg/kg/day to rats, with a total amount 10.12 mg, spontaneous activity was examined for about 37 weeks. Weaning male albino rats of Wistar strain, named (Tamura 1950) by closed colony, were used, and activity was investigated with a actphotometer (Natume KN-84 TN), at 20 different times, 2 hr per trial. Although rats were breeded for 50 weeks after weaning, it was found that body wt. of the group on As2O3 was statistically no less than that of control. There was no statistical difference in the spontaneous activity of rats between the above mentioned groups. Utilizing this form of administration of As2O3, differences regarding spontaneous activity were not observed between this group and control.

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