書誌事項
- タイトル別名
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- Ramsay Hunt Syndrome during Anti-Retroviral Therapy in an HIV-Seropositive Patient
- 臨床 治療中にハント症候群を発症したHIV感染症例
- リンショウ チリョウ チュウ ニ ハント ショウコウグン オ ハッショウ シタ HIV カンセン ショウレイ
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説明
<p>We report the case of an HIV-seropositive patient with Ramsay Hunt syndrome. A 55-year-old bisexual man diagnosed as being HIV-seropositive was started on anti-retroviral therapy (ART), because his CD4+T cell count had decreased to under 200/μL over a period of 2 months. A week after the start of ART, he was diagnosed as having Ramsay Hunt syndrome, based on the presence of herpes zoster oticus and a positive serological test for VZV antibody. We speculate that the facial palsy was associated with the immune reconstitution inflammatory syndrome (IRIS), as follows. The decrease of the CD4+T cell count induced reactivation of VZV in the geniculate ganglion, but facial palsy did not develop. With the reconstitution of the immune system associated with increase of the CD4+T cell count by the ART, the reactivated VZV in the geniculate ganglion elicited an inflammatory response; the associated release of cytokines caused injury to the facial nerve.</p>
収録刊行物
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- 耳鼻咽喉科臨床
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耳鼻咽喉科臨床 111 (2), 101-104, 2018
耳鼻咽喉科臨床学会
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390282679248599808
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- NII論文ID
- 130006328267
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- NII書誌ID
- AN00107089
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- ISSN
- 18844545
- 00326313
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- NDL書誌ID
- 028834507
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可