鼻副鼻腔に発生したverrucous carcinomaの2例

DOI Web Site Web Site 被引用文献1件 参考文献6件
  • 竹本 洋介
    山口大学大学院医学系研究科耳鼻咽喉科学分野
  • 広瀬 敬信
    山口大学大学院医学系研究科耳鼻咽喉科学分野
  • 沖中 洋介
    山口大学大学院医学系研究科耳鼻咽喉科学分野
  • 御厨 剛史
    山口大学大学院医学系研究科耳鼻咽喉科学分野
  • 奥田 剛
    宇部興産中央病院耳鼻咽喉科
  • 原 浩貴
    山口大学大学院医学系研究科耳鼻咽喉科学分野
  • 山下 裕司
    山口大学大学院医学系研究科耳鼻咽喉科学分野

書誌事項

タイトル別名
  • Two Cases of Nasal and Paranasal Verrucous Carcinoma
  • 臨床 鼻副鼻腔に発生したverrucous carcinomaの2例
  • リンショウ ハナ フクビコウ ニ ハッセイ シタ verrucous carcinoma ノ 2レイ

この論文をさがす

説明

Verrucous carcinoma originating from various sites has been reported since Ackerman first reported an intraoral case in 1948. Histologically, the tumor is composed of atypical low squamous epithelium showing papillary growth, with strong cornification; in regard to the differentiation grade, the tumor is a subtype of well differentiated squamous cell carcinoma. There are scarce reports from foreign countries of verrucous carcinoma arising in the rhinosinus. Extensive resection is necessary, but it is said to be generally associated with a good prognosis. There are many reports recommending against the use of radiotherapy as the treatment modality of first choice, because local control is insufficient and radiotherapy is associated with a high risk of anaplastic transformation of the tumor.<br/>We encountered two cases of verrucous carcinoma of the rhinosinus. Case 1 was a 44-year-old woman with verrucous carcinoma of the left frontal sinus, complicated by a brain abscess. Case 2 was a 78-year-old woman with verrucous carcinoma (T4aN0M0 Stage IVa) of the left nasal cavity, who was treated by radiation plus cetuximab therapy. This verrucous carcinoma showed strong EGFR expression, therefore, cetuximab was effective. There is a case following fatal course in verrucous carcinoma, and it is necessary to pay attention.

収録刊行物

被引用文献 (1)*注記

もっと見る

参考文献 (6)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ