- 【Updated on May 12, 2025】 Integration of CiNii Dissertations and CiNii Books into CiNii Research
- Trial version of CiNii Research Knowledge Graph Search feature is available on CiNii Labs
- 【Updated on June 30, 2025】Suspension and deletion of data provided by Nikkei BP
- Regarding the recording of “Research Data” and “Evidence Data”
Comparative evaluation of colorimetry, GLC and HPLC for the determination of urinary hippuric acid.
-
- HASEGAWA Kenji
- Center of Occupational Medicine, Tohoku Rosai Hospital
-
- SEIJI Kazunori
- Center of Occupational Medicine, Tohoku Rosai Hospital
-
- SHIOJIMA Shoji
- Center of Occupational Medicine, Tohoku Rosai Hospital
-
- KOIZUMI Akio
- Department of Environmental Health, Tohoku University School of Medicine
-
- IKEDA Masayuki
- Department of Environmental Health, Tohoku University School of Medicine
Search this article
Description
Human urine samples, 81 from the non-exposed, 36 from those with intensive exposures to tolueue, and 23 from the less intensively exposed, were analyzed for hippuric acid by colorimetry, gas liquid chromatography (GLC), and high perform-ance liquid chromatography (HPLC). The colorimetric method always gave higher values than the GLC method. In the case of the non-exposed, the value by the former method was more than double the value by the latter. When the colori-metric values were plotted on the abscissa against the GLC values on the ordinate, the slope of the calculated regression line was 0.444 for the non-exposed while it was 0.882 for the exposed. The value was higher as the exposure was more intensive.A conversion formula between colorimetric and GLC values was calculated from the values observed and it was y=x(1-1.78e-0.43x)+0.50 where x and y are the colorimetric and GLC values (mg/ml), respectively, with a correlation coefficient of 0.82. The equation is however not applicable when x is smaller than 0.6. The HPLC values essentially agreed with the GLC values, the regression line being y=0.993z+ 0.009 where y and z are the GLC and HPLC values (mg/ml), respectively. The correla-tion coefficient, r, was 0.994.
Journal
-
- Industrial Health
-
Industrial Health 17 (4), 215-221, 1979
National Institute of Occupational Safety and Health
- Tweet
Details 詳細情報について
-
- CRID
- 1390282679257387008
-
- NII Article ID
- 130003550350
-
- ISSN
- 18808026
- 00198366
-
- Text Lang
- en
-
- Data Source
-
- JaLC
- Crossref
- CiNii Articles
- OpenAIRE
-
- Abstract License Flag
- Disallowed