EXPERIMENTAL PULMONARY EDEMA IN RODENTS FOLLOWING A SINGLE INJECTION OF 4-NITROQUINOLINE 1-OXIDE
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- HAYASHI YUZO
- Shionogi Research Laboratory, Shionogi & Co., Ltd.
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- HASEGAWA TOSHIAKI
- Shionogi Research Laboratory, Shionogi & Co., Ltd.
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- KATAYAMA HIRO
- Shionogi Research Laboratory, Shionogi & Co., Ltd.
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Abstract
Administration of 4-nitroquinoline 1-oxide has been known to produce pulmonary tumors in rodents (1-3). An electron microscopic examination on the lung of rats shortly after an injection of this compound revealed induction of nucleolar segregation in the alveolar epithelial cells (4). In this experiment, it was further shown that an injection of 4-nitroquinoline 1-oxide could produce pulmonary edema in rats as well as in guineapigs and rabbits.
Journal
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- The Japanese Journal of Pharmacology
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The Japanese Journal of Pharmacology 20 (2), 264-271, 1970
The Japanese Pharmacological Society
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Keywords
Details 詳細情報について
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- CRID
- 1390282679265414272
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- NII Article ID
- 130000837367
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- NII Book ID
- AA00691188
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- COI
- 1:CAS:528:DyaE3cXks1Chtb0%3D
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- ISSN
- 13473506
- 00215198
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- NDL BIB ID
- 8509520
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- PubMed
- 5311563
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- Web Site
- http://id.ndl.go.jp/bib/8509520
- https://ndlsearch.ndl.go.jp/books/R000000004-I8509520
- https://api.elsevier.com/content/article/PII:S0021519819613387?httpAccept=text/xml
- https://api.elsevier.com/content/article/PII:S0021519819613387?httpAccept=text/plain
- https://search.jamas.or.jp/link/ui/1971045329
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed
