Pharmacological studies on cough reflex. Part 2, Cough depressing actions of various drugs

  • KASÉ YOSHITOSHI
    Department of Chemico-Pharmacology, Faculty of Pharmacy, Kumamoto University

書誌事項

タイトル別名
  • PHARMACOLOGICAL STUDIES ON COUGH REFLEX
  • PART 3. “COUGHING DOG” AND ITS APPLICATION

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説明

I gave out two methods (1) for evaluation of the effects of antitussives. In the initial stage of my experiment the cough attacks were induced in an unanesthetized dog either by mechanically stimulating with a bristled stimulator the mucous membranes of the tracheal bifurcation (method 1) or by electrically stimulating the ramus trachealis nervi laryngici cranialis (method 2). However, the bloody surgical procedures required in either method made it impossible to use the same dog in a series of experiments or to continue the daily administration of an antitussive over a long period of time for observation of possible changes in its effects. Accordingly, the methods have since been so improved as to make a continuous use of one and the same dog possible. The improved method, though the same in principle as method 1, differs from it in that the mechanical stimulation of the-tracheal bifurcation is given by a bristled stimulator through a cannula inserted into a tracheal fistula surgically produced prior to the experiment.

収録刊行物

  • Jpn.J.Pharmacol.

    Jpn.J.Pharmacol. 4 (2), 130-135, 1955

    公益社団法人 日本薬理学会

被引用文献 (3)*注記

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詳細情報 詳細情報について

  • CRID
    1390282679266602368
  • NII論文ID
    130000834661
    130000834660
  • DOI
    10.1254/jjp.4.130
    10.1254/jjp.4.118
    10.1016/s0021-5198(19)65212-1
  • COI
    1:STN:280:CymD38zgtVU%3D
    1:STN:280:CymD38zgtVQ%3D
  • ISSN
    13473506
    00215198
  • PubMed
    13270979
    13270978
  • 本文言語コード
    en
  • 資料種別
    journal article
  • データソース種別
    • JaLC
    • Crossref
    • PubMed
    • CiNii Articles
    • OpenAIRE
  • 抄録ライセンスフラグ
    使用不可

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