A Comparative Study on the Treatment of Herpes Zoster with Vidarabine or Acyclovir.

DOI 7 References

Bibliographic Information

Other Title
  • ビダラビンとアシクロビル（簡便法）の帯状ほう疹に対する治療効果の比較検討　帯状ほう疹後神経痛への効果を中心に
  • —帯状疱疹後神経痛への効果を中心に—

Description

Outpatients, over 40-years-old, with herpes zoster without any other immunosuppressive diseases were administered either Vidarabine at a dose of 300 mg/day (80 cases) or Acyclovir intravenously 500mg once a day, for 3 to 7 days (25 cases). A comparative study was then conducted on patients with persistent postherpetic neuralgia (PHA) for 30 days following the onset of the disease. The patients were divided into the two above groups and another group not given any antiviral compounds (51 cases). The ratios of PHN in the groups treated with Vidarabine and Acyclovir and those not given antiviral compounds were 25%, 24% and 29% respectively. These values did not differ statistically. Starting the administration of Vidarabine or Acyclovir within 5 days after the onset of the disease showed no noticeable effect in decreasing PHN. However, a higher incidence of PHN was noted in patients with a sleep disturbance due to herpetic neuralgia at the first visit as compared to patients without such a disturbance.

Journal

References(7)*help

See more

Keywords

Details 詳細情報について

  • CRID
    1390282679270935424
  • NII Article ID
    130004830771
  • DOI
    10.2336/nishinihonhifu.53.732
  • ISSN
    18804047
    03869784
  • Text Lang
    ja
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

Report a problem

Back to top