Therapeutic Effects of Coix Seed Extract (Yokuinin) on Persistent Condyloma Acuminatum.

  • TANIGUCHI Shoji
    Division of Dermatology, Osaka General Hospital of West Japan Railway Company
  • KONO Takeshi
    Department of Dermatology, Osaka City University Medical School
  • HOSOMI Naoko
    Department of Dermatology, Osaka City University Medical School
  • HIGASHI Natsuko
    Department of Dermatology, Osaka City University Medical School
  • YAMAMOTO Naoki
    Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry

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  • ヨクイニンによる難治性尖圭コンジロームの治療

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We investigated the clinical effects of a herbal medicine coix seed extract (Yokuinin) on eleven cases of condyloma acuminatum that were resistant to cryotherapy, electrocoagulation, or the local administration of bleomycin. The patients were treated with coix seed extract at 6.0 g/day p.o. for 12 weeks without receiving any other therapies. The treatment resulted in an effective improvement of the eruptions in eight patients (72.7%), including an excellent effect in three patients (27.3%). No serious side effects were noted. This indicated that coix seed extract therefore appears to be a useful treatment for condyloma acuminatum as well as verruca vulgaris.

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