Smoldering Type Adult T Cell Leukemia Associated with an Extensive Hypogammaglobulinemia
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- TAKANO Yoshika
- Department of Dermatology, Fukuoka University, School of Medicine
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- NISHIMURA Masayuki
- Department of Dermatology, Fukuoka University, School of Medicine
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- HAYASHI Noritaka
- Department of Dermatology, Fukuoka University, School of Medicine
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- TOSHITANI Shoji
- Department of Dermatology, Fukuoka University, School of Medicine
Bibliographic Information
- Other Title
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- 著明な低ガンマグロブリン血症を伴つたくすぶり型成人T細胞白血病
Description
We treated a Japanese man with adult T cell leukemia. He had been born at Sasebo and is now 44 years old. Asymptomatic red papules were seen in a disseminated pattern on the trunk and upper and lower extremities, and to some extent the papular eruptions fused to form irregular shaped plaques. Histologically, there was a dense infiltration of abnormal lymphocytes with a prominent nuclear atypism present in the upper dermis and some of those lymphoid cells infiltrated the epidermis and formed a microabscess. Immunohistological characterization of cell surface marker antigens revealed that the abnormal lymphoid cells were positive for OKT4, OKT11, Tac, Leu3a+3b and Leu4. Laboratory data: WBC 7,500/mm3, lymphocyte 10%, abnormal lymphocyte 1%, LDH 541 U/L, γ-globulin 0.58 g/dl, anti ATLA antibody ×130. To our knowledge, it is the association of such an extensive hypogammaglobulinemia in the smolderling type of adult T cell leukemia.
Journal
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- Nishi Nihon Hifuka
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Nishi Nihon Hifuka 49 (1), 50-55, 1987
Western Division of Japanese Dermatological Association
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Keywords
Details 詳細情報について
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- CRID
- 1390282679274657024
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- NII Article ID
- 130004473270
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- ISSN
- 18804047
- 03869784
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed