Smoldering Type Adult T Cell Leukemia Associated with an Extensive Hypogammaglobulinemia

DOI 4 References

Bibliographic Information

Other Title
  • 著明な低ガンマグロブリン血症を伴つたくすぶり型成人T細胞白血病

Abstract

We treated a Japanese man with adult T cell leukemia. He had been born at Sasebo and is now 44 years old. Asymptomatic red papules were seen in a disseminated pattern on the trunk and upper and lower extremities, and to some extent the papular eruptions fused to form irregular shaped plaques. Histologically, there was a dense infiltration of abnormal lymphocytes with a prominent nuclear atypism present in the upper dermis and some of those lymphoid cells infiltrated the epidermis and formed a microabscess. Immunohistological characterization of cell surface marker antigens revealed that the abnormal lymphoid cells were positive for OKT4, OKT11, Tac, Leu3a+3b and Leu4. Laboratory data: WBC 7,500/mm3, lymphocyte 10%, abnormal lymphocyte 1%, LDH 541 U/L, γ-globulin 0.58 g/dl, anti ATLA antibody ×130. To our knowledge, it is the association of such an extensive hypogammaglobulinemia in the smolderling type of adult T cell leukemia.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 49 (1), 50-55, 1987

    Western Division of Japanese Dermatological Association

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Details 詳細情報について

  • CRID
    1390282679274657024
  • NII Article ID
    130004473270
  • DOI
    10.2336/nishinihonhifu.49.50
  • ISSN
    18804047
    03869784
  • Text Lang
    ja
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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