Allergic Contact Blepharoconjunctivitis due to Phenylephrine Hydrochloride Eye Drops.

DOI 1 Citations 7 References

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Other Title
  • 塩酸フェニレフリンによるアレルギー性接触眼けん結膜炎の１例

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Description

A 68-year-old man developed conjunctival hyperemia, pruritus and bilateral palpebral edema, whenever he underwent an ophthalmologic examination with Mydrin®-P eye drops as a mydriatic agent. Similar symptoms arose an hour after the administration of Neosynesin® eye drops. The conjunctivitis continued for over a month despite treatment with Tarivit®, Ecolicin® and Sulperin® eye drops, and resolved a week after all eye drop medication was stopped. Skin prick tests and patch tests showed positive reactions to phenylephrine hydrochloride, which was a major ingredient of Mydrin®-P and Neosynesin®. Positive patch test reactions to phenylephrine hydrochloride were stronger after 7 days than after 72 hours, and persisted for more than 3 weeks. Our findings suggest that the allergic contact reactions due to phenylephrine hydrochloride in our patient were related to not only delayed-type hypersensitivity reactions but also to immediate-type hypersensitivity reactions.

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Details 詳細情報について

  • CRID
    1390282679274862976
  • NII Article ID
    130004474779
  • DOI
    10.2336/nishinihonhifu.64.281
  • ISSN
    18804047
    03869784
  • Text Lang
    ja
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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