A Case of Dermatomyositis with Exacerbation by Cytomegalovirus Infection

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  • AKIYAMA Yuichiro
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • OGAWA Fumihide
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • SATO Shinichi
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • SUEYOSHI Fumiko
    Division of Dermatology, Nagasaki Ekisaikai Hospital

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Other Title
  • サイトメガロウイルス感染症にて増悪した皮膚筋炎の１例
  • 症例 サイトメガロウイルス感染症にて増悪した皮膚筋炎の1例
  • ショウレイ サイトメガロウイルス カンセンショウ ニテ ゾウアクシタ ヒフ キンエン ノ 1レイ

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Description

We report an 80-year-old female with dermatomyositis. When she visited our hospital, she had experienced general malaise with muscle weakness, poikiloderma of the upper chest, and edematous erythema with itching on the neck and waist. Dermatomyositis was diagnosed according to skin biopsy of the neck lesion, thigh MRI, and blood examinations. After daily administration of 40 mg of oral corticosteroid, symptoms and laboratory data improved. However, exacerbation of the erythema and an increased level of aldolase were observed to be caused by cytomegalovirus infection that was revealed by cytomegalovirus antigenemia assay. Intravenous infusion of Ganciclovir 5 mg/kg for 14 days improved skin lesions and laboratory data, and dosage of corticosteroid was reduced. Cytomegalovirus infection is suggested to be involved in the exacerbation of dermatomyositis in this case.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 69 (6), 601-604, 2007

    Western Division of Japanese Dermatological Association

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