Clinico-pathologic studies of cutaneous metastasis from carcinoma of the breast.

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  • 乳癌の皮膚転移の２例

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Two cases with cutaneous metastatic lesions from carcinoma of the breast are presented. A 47-year-old woman suffered from dimpling of the skin and retraction of the nipple with an underlying saucer-like induration of the left breast of six months’ duration. Histopathologically, the lesion was diagnosed as infiltrating duct carcinoma of the breast, whereby the tumor cells infiltrated between the collagen bundles in the middle to deep dermis. In the upper dermis, there was a diffuse invasion of smaller groups of tumor cells arranged in poorly differentiated ductal and alveolar structures. The other case was an 80-year-old woman who had reddish nodular masses on the upper inner quadrant of the right breast. Histopathologic examinations revealed hyperchromatic tumor cells infiltrating the whole dermis, arranged in alveolar structures. The nuclei were uniform in size and shape and displayed only a small number of mitotic figures. This case was diagnosed as scirrhous carcinoma of the breast.

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