A Morphea-like Lesion Regarded as an Early Manifestation of Systemic Sclerosis in a Child

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  • TAMAI Mariko
    Department of Dermatology, Field of Sensory Organology, Graduate School of Medical and Dental Sciences, Kagoshima University
  • HIGASHI Yuko
    Department of Dermatology, Field of Sensory Organology, Graduate School of Medical and Dental Sciences, Kagoshima University
  • KAWAI Kazuhiro
    Department of Dermatology, Field of Sensory Organology, Graduate School of Medical and Dental Sciences, Kagoshima University
  • KANEKURA Takuro
    Department of Dermatology, Field of Sensory Organology, Graduate School of Medical and Dental Sciences, Kagoshima University
  • NISHI Masayuki
    Nishi Dermatoplastic Surgery Clinic

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Other Title
  • モルフェア様の皮膚硬化を呈し全身性強皮症への移行が強く疑われた小児の１例
  • 症例 モルフェア様の皮膚硬化を呈し全身性強皮症への移行が強く疑われた小児の1例
  • ショウレイ モルフェアヨウ ノ ヒフ コウカ オ テイシ ゼンシンセイ キョウヒショウ エ ノ イコウ ガ ツヨク ウタガワレタ ショウニ ノ 1レイ

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Description

A 7-year-old girl was referred to our department with an irregularly shaped pigmented lesion, 10 × 7 cm in size, that had appeared on her lower right leg 4 years earlier. Physical examination on her first visit revealed the lesion to be sclerotic. A biopsy specimen showed dense collagen bundles. With these findings, we first considered it as morphea. However, Raynaud's phenomenon and elongation of nailfolds with capillary changes turned out to be apparent and laboratoryexamination showed a positive anti-topoisomerase I antibody. Based upon these findings, we regarded that her skin lesion was an early manifestation of systemic sclerosis. General examinations including chest plain X-ray, CT, and electro- and echocardiography disclosed no abnormal findings. She is under our careful observation.

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