Utility of Antifungal Ointment Ketoconazole Cream in Treating Seborrheic Dermatitis. A Comparison with Ibuprofen Piconol Cream.

DOI 7 References

Bibliographic Information

Other Title
  • 脂漏性皮膚炎における外用抗真菌剤ケトコナゾールの有用性の検討　　イブプロフェンピコノールクリームとの比較
  • —A Comparison with Ibuprofen Piconol Cream—
  • —イブプロフェンピコノールクリームとの比較—

Search this article

Description

For the treatment of seborrheic dermatitis, a topical steroids have been widely used in Japan. In western countries, howerer, an antifungal agent ketoconazole (Nizoral® cream) has been found to be very useful in treating this disease. In recent clinical trials in Japan, 70-80% improvement has been reported when using this agent. In the present study, 54 seborrheic dermatitis patients with facial lesions were treated with both ketoconazole cream and nonsteroidal antiinflammatory drug ibuprofen piconol (Staderm®cream), and the effects of these two agents were compared. For the ketoconazole treated arms, the cure rate, improvement rate, and utility rate were 59%, 93% and 93% respectively. For the ibuprofen piconol treated arm, the rates were 8%, 56% and 56% respectively, and significant differences were observed between the two agents. Based on these findings, ketoconazole cream is therefore considered to be more useful than ibuprofen piconol cream for the treatment of seborrheic dermatitis.

Journal

References(7)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top