Uric Acid Levels in Psoriasis Vulgaris

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  • 尋常乾癬の血清尿酸値
  • ジンジョウカンセン ノ ケッセイ ニョウサンチ

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Allopurinol was administered to 31 patients with various forms of psoriasis, 16 being males and 15 females. The average uric acid in this group was 5.92±1.71 mg/dl, which was whithin the variation of healthy persons. Allopurinol decreased uric acid with hyperuricemia to the normal level when administration continued for 2 months. As to the course of psoriatic lesions, allopurinol produced the following results; good results in 5 cases, no change in 5 cases and worsening in 1 case. No serious side effects were observed, while 1 case showed gastrointestinal disturbances. In the discussion of hyperuricemia in psoriasis, the author considered that it depended upon the hyperproduction of uric acid in purine metabolism.

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