A Case of Eruptive Xanthoma with Severe Type V Hyperlipidemia

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  • 著明なＶ型高脂血症を伴った発疹性黄色腫の１例

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Abstract

We report a case of 42-year-old male with eruptive xanthoma. He noticed skin eruption on his right forearm at first. The skin eruption spread over his whole body within 5 days. The skin eruption consisted of numerous yellowish and reddish papules on his trunk and extremities, especially on his elbows and knees. He had been treated for schizophrenia from the age of 25. The laboratory findings showed glycosuria (+++) and an increased level of triglyceride 12080 mg/dl, total cholesterol 1080 mg/dl, chylomicron (++), LDL 1900 mg/dl, VLDL 3500 mg/dl, glucose 420 mg/dl and HbA1C 16.5%. The histopathological examination revealed a mass of foam cells and perivascular infiltration of inflammatory cells in the dermis. The patient had a diagnosis of eruptive xanthoma with severe type V hyperlipidemia and diabetes mellitus. We treated this patient with diet therapy, antilipemic and antidiabetic drugs. Seven months later, the papules almost disappeared. Abnormal dietary habit due to schizophrenia and pharmacological action of antipsychotic drug caused hyperlipidemia with eruptive xanthoma.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 66 (2), 135-137, 2004

    Western Division of Japanese Dermatological Association

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