A Case of Congenital Cutaneous Candidiasis with Slight Elevation of Serum .BETA.-D Glucan

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  • SHINOGI Taro
    Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University
  • NAKAFUSA Junji
    Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University
  • MIURA Yoshihiro
    Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University
  • MISAGO Noriyuki
    Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University
  • NARISAWA Yutaka
    Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University
  • NISHI Masanori
    Department of Pediatrics, Faculty of Medicine, Saga Universit
  • HAMASAKI Yuhei
    Department of Pediatrics, Faculty of Medicine, Saga Universit
  • NISHIMOTO Katsutaro
    Ekisaikai Nagasaki Hospital of Japan Seafarers Relief Association

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Other Title
  • β‐Ｄグルカン値の軽度上昇を伴った先天性皮膚カンジダ症の１例
  • 症例 β-Dグルカン値の軽度上昇を伴った先天性皮膚カンジダ症の1例
  • ショウレイ ベータ Dグルカンチ ノ ケイド ジョウショウ オ トモナッタ センテンセイ ヒフ カンジダショウ ノ 1レイ

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Abstract

We report a case of congenital cutaneous candidiasis in a 2526 g female infant born at 37 weeks and 6 days of gestation without newborn asphyxia or muddiness of the amniotic fluid. Many scales and erythemas and some pustules were noted on her trunk and extremities at birth. Direct KOH examination of the scales revealed pseudomycelia and spores. Candida albicans was identified by slide cultures from the scales. Values for all examinations (including blood examinations, chest X-ray and ultrasound tomography) were nearly normal. She was treated with topical application of terbinafine hydrochloride cream. However, blood examination showed a slight elevation of CRP and β-D-glucan after one day. Therefore, she was intravenously administered fluconazole. She recovered completely without evidence of recurrent candidiasis.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 67 (1), 38-41, 2005

    Western Division of Japanese Dermatological Association

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