Parvovirus B19 Infection Associated with Joint and Muscle Involvement. An Outbreak among Hospital Staffs and Inpatients.

DOI 10 References
  • MAEKAWA Yoshihiro
    Faculty for Clinical Research, Department of Dermatology, Kumamoto National Hospital
  • KOGUSHI Hazuki
    Faculty for Clinical Research, Department of Dermatology, Kumamoto National Hospital
  • KUNITAKE Yuko
    Faculty for Clinical Research, Department of Dermatology, Kumamoto National Hospital

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Other Title
  • 関節・筋症状および皮疹を伴ったパルボウイルスＢ１９感染症　　院内職員・患者に発症した症例の検討
  • —An Outbreak among Hospital Staffs and Inpatients—
  • —院内職員·患者に発症した症例の検討—

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An outbreak of parvovirus B 19 (PVB 19) infection occurred at our hospital, infecting both staffs and inpatients. Clinically, the rash differed from those of typical erythema infectiosum in adult patients, and 12 of 14 cases had either papular or reticular erythema and purpura on their extremities. In addition, arthralgia, myalgia, headache and malaise occurred in some patients. The clinical diagnosis was difficult because the rash and infectious seasons of PVB 19 infection and rubella are quite similar. Three blood samples from fourteen patients were examined for anti-PVB-specific IgM and IgG antibodies and they were also tested for PVB 19-DNA by the polymerase chain reaction, and all showed positive results.

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