A Case of Contact Dermatitis due to Fiblast Spray, a Product of Basic Fibroblast Growth Factor

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Other Title
  • フィブラストスプレー（ｂＦＧＦ製剤）による接触皮膚炎の１例
  • 症例 フィブラストスプレー(bFGF製剤)による接触皮膚炎の1例
  • ショウレイ フィブラストスプレー bFGF セイザイ ニ ヨル セッショク ヒフエン ノ 1レイ

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Abstract

A 38-year-old Japanese man had been treated with Fiblast® spray, a product of recombinant human basic fibroblast growth factor, for a skin ulcer after open reduction of a fractured calcaneum. The skin ulcer did not improve well and was associated with desquamative erythema. We observed a positive reaction on patch test against benzalconium chloride, which is included as a preservative in Fiblast® spray. Benzalconium chloride is known to provoke contact dermatitis. We should exercise caution with Fiblast® spray because of its potential to cause contact dermatitis.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 68 (3), 248-250, 2006

    Western Division of Japanese Dermatological Association

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