A Case of a Granular Cell Tumor

DOI 10 References
  • KOBAYASHI Junichi
    Division of Dermatology, Kyushu Kousei nenkin Hospital
  • NAKANO Ryuji
    Division of Pathology, Kyushu Kousei nenkin Hospital
  • KIRYU Hiromaro
    Division of Dermatology, Kitakyushu Municipal Medical Center
  • FUKIWAKE Noriko
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University
  • FURUE Masutaka
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University

Bibliographic Information

Other Title
  • か粒細胞腫の１例

Abstract

We herein report a case of a granular cell tumor at the nape of the neck of a 53-year-old female. Immunohistological studies showed the tumor cells to be positive for S-100 protein, neuron specific enolase (NSE), vimentin, α1-antichymotrypsin, and CD68, but negative for α-smooth muscle actin (SMA) and HHF-35. Transmission electron microscopy indicated that ultrastructurally the tumor cells had a basement membrane and lysosomal granules in their cytoplasm. Angulated bodies, which are usually seen in schwannoma, were observed scattered throughout the cytoplasm of some tumor cells. Some parts of the peripheral nervous system, including axons, were observed in the tumor. These results indicated that this tumor originated from a tissue consisting of schwann cells. Because these tumor cells were positive for α1-antichymotrypsin and CD68 an analysis of lysosomes will be central to all future pathological identification.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 65 (5), 451-454, 2003

    Western Division of Japanese Dermatological Association

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Keywords

Details 詳細情報について

  • CRID
    1390282679276626432
  • NII Article ID
    130004474939
  • DOI
    10.2336/nishinihonhifu.65.451
  • ISSN
    18804047
    03869784
  • Text Lang
    ja
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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