The Diagnosis of Subungual Malignant Melanoma in the Early Stage

  • GOTO Mayuko
    Department of Dermatology, Faculty of Medicine, Oita University
  • MATSUDA Haruna
    Department of Dermatology, Faculty of Medicine, Oita University
  • ITO Yukako
    Department of Dermatology, Faculty of Medicine, Oita University
  • KAI Yoshitaka
    Department of Dermatology, Faculty of Medicine, Oita University
  • GOTO Mizuki
    Department of Dermatology, Faculty of Medicine, Oita University
  • HATANO Yutaka
    Department of Dermatology, Faculty of Medicine, Oita University
  • KATAGIRI Kazumoto
    Department of Dermatology, Faculty of Medicine, Oita University
  • FUJIWARA Sakuhei
    Department of Dermatology, Faculty of Medicine, Oita University
  • KATO Aiko
    Department of Plastic Surgery, Faculty of Medicine, Oita University
  • SHIMIZU Fumiaki
    Department of Plastic Surgery, Faculty of Medicine, Oita University
  • YOKOYAMA Shigeo
    Department of Diagnostic Pathology, Faculty of Medicine, Oita University

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Other Title
  • 爪甲下悪性黒色腫初期病変の診断
  • 症例 爪甲下悪性黒色腫初期病変の診断
  • ショウレイ ソウコウ カ アクセイ コクショク シュ ショキ ビョウヘン ノ シンダン

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Description

A 66-year-old man presented with a dark brown-colored pigment line on his right fourth fingernail for five months. The width of the line was 3.8 mm. The color and shade of the line varied from light to dark, and Hutchinson sign was not observed. Because of irregular lines in dermoscopy, we suspected malignant melanoma, and excisional biopsy was performed. Biopsy specimens showed that atypical melanocytes had formed small nests. A diagnosis of malignant melanoma in situ was made. A 60-year-old woman visited us because of a blackish brown-colored line in her right first toenail for two years. The width of the line was 5 mm. The line had some lightly colored parts. Excisional biopsy specimens showed proliferation of atypical melanocytes, and a diagnosis of malignant melanoma in situ was made. Subungual malignant melanoma in the early stage is difficult to diagnose. We are often at a loss whether to perform surgery or not. We propose an algorithm to distinguish subungual malignant melanoma from longitudinal melanonychia.

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